Results 141 to 150 of about 85,673,309 (349)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Celebrating 10 years of the Irish Health Research Forum 2014-2024 [PDF]
This is a brief overview of the success of the Irish Health Research Forum over 10 years since its foundation in ...
Health Research Charities Ireland
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Conceptual Framework for Religiousity Survey in Iran [PDF]
In analyzing the complex issue of religion, social science researchers require an operational definition aside from the logical and conceptual definitions of religion and religiousity.
Mohammad Reza Taleban
doaj
Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Evaluating Online Labor Markets for Experimental Research: Amazon.com's Mechanical Turk
Adam J. Berinsky +2 more
semanticscholar +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Anales de la Estación Experimental de Aula Dei 15 (3-4)
98 Págs. Índice: Incluye en preliminar obituario Don Luis-María Villena Martín (1920-1981). Índice: An analysis on the distribution of the Indian taxa of the genus Primula Linn., in the eastern Himalaya with remarks on the species of Assam / Ghosh ...
CSIC - Estación Experimental de Aula Dei (EEAD)
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