Results 121 to 130 of about 42,438,687 (307)
Health Research in Action 2023
, 2023 This year’s Health Research in Action highlights some of the many notable impacts and outcomes of our work. It includes a snapshot in numbers of all work completed in 2022, followed by 29 success stories about wide-ranging health and social care research
Health Research Board
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Celebrating 10 years of the Irish Health Research Forum 2014-2024 [PDF]
This is a brief overview of the success of the Irish Health Research Forum over 10 years since its foundation in ...
Health Research Charities Ireland
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The damping system for floating caisson of С-1 navigation pass of St.-Petersburg flood protection barrier [PDF]
Инженерно-строительный журнал, 2012 Floating caisson of navigation pass C-1 is designed for shutdown in case of threat of flooding the main ship canal in St.-Petersburg flood protection barrier.
A.S. Bolshev +3 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Biobanking in Ireland: Moving Forward. Irish Health Research Forum Recommendations and Event Report [PDF]
This report presents the proceedings of the Irish Health Research Forum on November 16th 2023, focusing on progressing biobanking in Ireland, and makes key recommendations for moving biobanking forward.Roche Products ...
Health Research Charities Ireland
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A Conceptual Framework for Religiousity Survey in Iran [PDF]
Islām va ̒ulūm-i ijtimā̒īIn analyzing the complex issue of religion, social science researchers require an operational definition aside from the logical and conceptual definitions of religion and religiousity.
Mohammad Reza Taleban
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Medical Research Charities Group: Annual report 2018 [PDF]
, 2019 2018 was a year of high activity and much progress for the MRCG. Fourteen exciting research projects were funded through our Joint Funding Scheme with the HRB, two impactful Irish Health Research Forum events were held and we did much to support our ...
Medical Research Charities Group
core +1 more source