Results 251 to 260 of about 58,403,547 (305)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Exploration of Experimental Research and Molecular Dynamics Simulation on the Adsorption and Desorption Characteristics of Gas-Bearing Coal with Water-Based Mucilage Suppression. [PDF]

ACS Omega
Jin W, Xu Y, Li Z, Zhang X.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Analytical and Experimental Research of Lubrication Load-Bearing Characteristics of Microtextured Meshing Interface. [PDF]

Materials (Basel)
Wang X, Ruan J, Wang Y, Zou W.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Experimental research on resource utilization of iron tailings powder in backfilling engineering. [PDF]

Sci Rep
Yuan GH, Yao YS, Zhang PG, Hao WG, Huang KP, Jin-Li, Shang QF.   +6 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Analgesic Effect of Morphine on Peripheral Opioid Receptors: An Experimental Research. [PDF]

J Crit Care Med (Targu Mures)
Jafal NM, Stoleru S, Zugravu A, Orban C, Popescu M, Marin RC, Fulga IG.   +6 more
europepmc   +1 more source

Experimental research on fungal inhibition using dissolving microneedles of terbinafine hydrochloride nanoemulsion for beta-1,3-glucanase. [PDF]

Nanoscale Adv
Wang H, Wang Y, Liu J, Qi Y, Sun W, Qiu H, Zhang Y, Ping Y.   +7 more
europepmc   +1 more source

The protective effect and experimental research progress of pleotropic statins in intervertebral disc degeneration. [PDF]

J Orthop Surg Res
Zhang X, Li S, Liu X, Ma Z, Zhang Q, Zhang Y, An J, Luo Z.   +7 more
europepmc   +1 more source