Results 181 to 190 of about 10,661,924 (343)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Experimental research on mechanical and microstructural characteristics of hybrid fiber reinforced concrete (HFRC). [PDF]

Sci Rep
Vadivel M, Selinaruby G, Padmapriya R, Perumal B.   +3 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research and experimental activities related to conifers in the mediterranean area. Abstract

, 2008
Paraskevi Alizoti, Michel Bariteau, Fulvio Ducci, Bruno Fady, Ernesto Fusaro, Christian Pichot   +5 more
openalex   +1 more source

Experimental research on instability mechanism of silty mudstone roofs under action of water and its application

, 2009
Qiangling Yao, Futao Zhang, Xiaolei Ding, Lei Zhang, Guang Jiang   +4 more
openalex   +1 more source

Experimental Research on the Ecological Recovery of Metals from Used Ni-MH Batteries. [PDF]

Materials (Basel)
Ghica VG, Miculescu F, Vasile A, Saftere ND, Markopoulos AP, Karabulut Ș, Petrescu MI, Tanasă E, Icleanu A.   +8 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Improvement of Crawl Stroke for the Swimming Humanoid Robot to Establish an Experimental Platform for Swimming Research

, 2015
Motomu NAKASHIMA, Yuto TSUNODA
openalex   +1 more source

Effect sizes for experimental research. [PDF]

Br J Math Stat Psychol
Hedges LV.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source