Results 131 to 140 of about 59,278,538 (306)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

El gusto por las reposiciones [PDF]

, 1946
Cine experimental (1946). El gusto por las reposiciones. Cine experimental. (10):185-185.
Cine experimental
core  

The methodology of multi objective design of active-passive shielding system for overhead power lines magnetic field in residential buildings space based on metaheuristic optimization method

Electrical engineering & Electromechanics
Problem. Most studies of power frequency magnetic field reduced to safe level in in residential buildings located near overhead power lines carried out based on passive or active electromagnetic shielding, but there is no methodology for designing active-
B. I. Kuznetsov, A. S. Kutsenko, T. B. Nikitina, I. V. Bovdui, K. V. Chunikhin, V. V. Kolomiets   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Experimental Animal in Research [PDF]

Nature, 1964
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Health Research Board: Health Research in Action [PDF]

This year’s Health Research in Action highlights some of the many notable impacts and outcomes of our work. It includes a snapshot in numbers of recent work completed, followed by 19 success stories about wide-ranging health and social care research ...
Health Research Board
core  

Películas españolas [PDF]

, 1945
Cine experimental (1945). Películas españolas. Cine experimental. (4):252-254.
Cine experimental
core  

Simulation and Experimental Research of Air Conditioning and Ventilating System for Intercity Train

机车电传动, 2020
In intercity vehicle, the air conditioning and ventilation system has an important impact on breeze speed, temperature and humidity of which directly affects the thermal comfort of passengers.
Shujuan SUN, Xin LIN
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source