Results 41 to 50 of about 5,472,250 (305)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Experiences and results with a cementless femoral stem design: SL-PLUS MIA

open access: yes, 2023
Aim: To evaluate the outcomes of the SL-PLUS® MIA cementless femoral stem (Smith & Nephew Orthopedics AG, Switzerland) application using the modified lateral approach. Method: Demographic and clinical data, in addition to the operational outcomes of 42
Köken, Murat   +6 more
core   +2 more sources

The FEA and experimental stress analysis in circular perforated plates loaded with concentrated force

open access: yesFracture and Structural Integrity, 2020
. The paper presents an analysis of an isotropic circular axisymmetric perforated plate loaded with concentrated force Pi applied in the geometric center of the plate using finite element software ANSYS.
Mateusz Konieczny   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The Bearing Capacity Model of Pile Foundation with Hole-Drilling and Pile-Inserting Technology in Complex Geological Environments

open access: yesBuildings
Karst geology creates a complex environment with diverse landforms, blurred boundaries, and multi-factor interactions. This paper presents a new drilling pile installation method: drill to a set depth, clean the hole, insert prefabricated piles, and ...
Yi Wang   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Biphasic Double-Network Hydrogel With Compartmentalized Loading of Bioactive Glass for Osteochondral Defect Repair

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Periarticular injury usually causes the defects of superficial cartilage and the underlying subchondral bone. Although some efficacious outcomes have been achieved by the existing therapeutic methods both in clinics and research, like symptomatic ...
Bingchuan Liu   +17 more
doaj   +1 more source

Experimental researches in electricity [PDF]

open access: yesAbstracts of the Papers Printed in the Philosophical Transactions of the Royal Society of London
Abstract This paper is divided into four parts: the first being on the Induction of Electric Currents; the second, on the Evolution of Electricity from Magnetism; the third, on a new Electrical Condition of Matter; and the fourth, on Arago’s Magnetic Phænomena.
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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