Results 251 to 260 of about 5,473,628 (305)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

A multifaceted investigation into the impact of m6A methylation-related genes on pancreatic cancer, integrating insights from various databases and foundational experimental research. [PDF]

Ann Med Surg (Lond)
Wen Y, Liu Z, Chen Y.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cognitive Activity of an Individual Under Conditions of Information Influence of Different Modalities: Model and Experimental Research. [PDF]

Entropy (Basel)
Petukhov AY, Morozov NS, Krasnitskiy NV, Petukhov YV.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Comparative Study of Injected Alzheimer's Disease Models in Rats: Insights from Experimental Research. [PDF]

Pathophysiology
Doumar H, El Mostafi H, Elhessni A, Laaziz A, Mesfioui A.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Editorial: The current state of knowledge on asthma-COPD overlap (ACO) in clinical and experimental research: what do we know so far? [PDF]

Front Immunol
Degobbi Tenorio Quirino Dos Santos Lopes F, Tibério IFLC, Fraga Righetti R.   +2 more
europepmc   +1 more source

Experimental Research on Gradation Range and Performance of SMAC13. [PDF]

Materials (Basel)
Zhen Q, Cao W, Dong R, Liu S, Liu N, Zhan Z, Li Y.   +6 more
europepmc   +1 more source

An undergraduate experimental research program, involving the screening of efflux pump inhibitors, to improve student research skills in biomedical science. [PDF]

BMC Med Educ
Zong G, Zhang P, Wang Y, Han J, Wang L, Pan J, Pang J, Cao G, Fu J.   +8 more
europepmc   +1 more source