Results 151 to 160 of about 8,711,360 (296)

Human cytomegalovirus infection and cognitive decline: insights from population and experimental studies. [PDF]

Front Aging Neurosci
Yaiw KC, Ferrer IA, Söderberg-Nauclér C, Religa D.   +3 more
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

EVOLUTION OF THE ETHNOSPECIFIC CONCEPT FLEISS (DILIGENCE) IN THE GERMAN LINGUISTIC CULTURE

Многоязычие в образовательном пространстве
The paper represents the analysis of the ethnospecific concept Fleiß in the German linguistic culture, it aims at studying the evolution of the concept .
T.S. Medvedeva, D.I. Medvedeva
doaj  

Geometric Analysis and Experimental Studies of Hexachiral Structures. [PDF]

Materials (Basel)
Plewa J, Płońska M, Feliksik K, Junak G.   +3 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Revisiting <i>Acalypha</i> medicinal interest: ethnobotany, experimental studies, and the implications of taxonomic misuse pitfalls. [PDF]

PhytoKeys
Villaescusa-González L, Cardiel JM, Montero-Muñoz I, Muñoz-Rodríguez P.   +3 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Nipple stimulation for labour augmentation: evidence from randomised and quasi-experimental studies. [PDF]

BMC Pregnancy Childbirth
Videgård M, Anderberg L, Wells MB.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

hnRNP A2B1 as a promising therapeutic target for radiomodulatory drug development: evidence from computational and experimental studies. [PDF]

Front Pharmacol
Lubinets NS, Tonkii IS, Sazonova VA, Dutta K, Putintseva AE, Volkova OO, Skorb EV, Zun P, Ruzov A, Kravtsov VY, Shityakov S.   +10 more
europepmc   +1 more source