Results 231 to 240 of about 8,711,360 (296)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

PAI1 regulating CHRNA1 contributes to primary focal hyperhidrosis: Clinical and experimental studies. [PDF]

Mol Ther Nucleic Acids
Zheng RJ, Lin NL, Zhang ML, Qiu RQ, Yu FQ, Li X, Lin JB.   +6 more
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Descriptive norms nudge meaningful engagement for the third age: two experimental studies. [PDF]

Sci Rep
Zhao L, Yin J, Zeng W.
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Identification and validation of novel risk genes for intervertebral disc disorder by integrating large-scale multi-omics analyses and experimental studies. [PDF]

Front Med (Lausanne)
Zhang Z, Chen Y, Wang Q, Li Z, Dai B, Dong C, Zhu Z.   +6 more
europepmc   +1 more source

Values interact with psychological distance and eco-anxiety to promote climate engagement: insights from two experimental studies. [PDF]

Front Psychol
Zhang H, Xu W, McCauley M.
europepmc   +1 more source

Is CONSORT a Risk of Bias Tool for Experimental Studies: A Big Misunderstanding. [PDF]

J Caring Sci
Sarbazi E, Sadeghi-Bazargani H.
europepmc   +1 more source

Sexual Dimorphism in Abdominal Aortic Aneurysm-Insights from Clinical and Experimental Studies. [PDF]

J Vasc Dis
Islam ZH, Mei H, Tetz Z, Kanchetty R, Stanisic S, Hoyt N, Marcum WA, Johnston C, Kent EW, Zhang M, Islam N, Anand A, Zhang K, Yin L, Wang B.   +14 more
europepmc   +1 more source

Participant Experience of Taking Part in Periodontal Experimental Studies. [PDF]

Int J Dent
Wu YC, Schumacher FL, Tatakis DN.
europepmc   +1 more source