Results 101 to 110 of about 1,479,949 (267)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Vineyard Pruning Extracts as Natural Antioxidants for Biodiesel Stability: Experimental Tests and Preliminary Life Cycle Assessment. [PDF]

ACS Sustain Chem Eng, 2023
Dorosh O, Surra E, Eusebio M, Monteiro AL, Ribeiro JC, Branco NFM, Moreira MM, Peixoto AF, Santos LMNBF, Delerue-Matos C.   +9 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Numerical and Experimental Study of the Impeller of a Liquid Pump of a Truck Cooling System and the Development of a New Open-Type Impeller

Tehnički Glasnik, 2020
Typically, closed-type impellers are more efficient than open-type impellers, but in the manufacture of closed-type impellers, cost of wheels is higher. This paper describes the development of cost-effective and simple impeller wheel for a fluid pump in ...
Rishat Salakhov, Andrey Ermakov, Elvira Gabdulkhakova   +2 more
doaj  

Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator. [PDF]

Elife, 2022
Phillips RS, Koizumi H, Molkov YI, Rubin JE, Smith JC.   +4 more
europepmc   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Experimental Investigation and Numerical Analysis of the Axial Load Capacity of Circular Concrete-Filled Tubular Columns

Buildings
This paper focuses on the experimental investigation of the axial load capacity of CFT (concrete-filled steel tube) columns under actual construction conditions during building reconstruction. A total of four samples were loaded up to failure. The varied
Marija M. Lazović Radovanović, Jelena Z. Nikolić   +1 more
doaj   +1 more source

Experimental Tests and Numerical Simulations on the Ballistic Impact Response of a Highly Inhomogeneous Aluminium Foam. [PDF]

Materials (Basel), 2022
Brekken KA, Vestrum O, Dey S, Reyes A, Børvik T.   +4 more
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Experimental Tests for Measuring Individual Attentional Characteristics in Songbirds. [PDF]

Animals (Basel), 2021
Pougnault L, Cousillas H, Heyraud C, Huber L, Hausberger M, Henry L.   +5 more
europepmc   +1 more source