Results 81 to 90 of about 1,479,949 (267)

New Makeup Air Method through Ceiling for Kitchen Ventilation in Severely Cold Regions and Its Effect on Air Environment

open access: yesAtmosphere
Severely cold weather reduces the willingness of residents to open windows while cooking. This results in an insufficient replenishment of makeup air and a reduction in the range hood discharge capacity.
Xiaoxu Li   +5 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

2D Conduction Simulation of a PCM Storage Coupled with a Heat Pump in a Ventilation System

open access: yesApplied Sciences, 2016
Efforts to simulate heat transfer in a PCM (Phase Change Material) storage device are generally led by considerations of Biot number and material thickness, of 2D versus 1D representation, and of possible hysteresis effects arising from the ...
Joseph Virgone, Abdelkrim Trabelsi
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanical Behaviour of Plantar Adipose Tissue: From Experimental Tests to Constitutive Analysis. [PDF]

open access: yesBioengineering (Basel), 2023
Pettenuzzo S   +9 more
europepmc   +1 more source

Experimental tests of asymptotic freedom [PDF]

open access: yesProgress in Particle and Nuclear Physics, 1997
Quantum Chromodynamics (QCD), the gauge field theory of the Strong Interaction, has specific features, asymptotic freedom and confinement, which determine the behaviour of quarks and gluons in particle reactions at high and at low energy scales. QCD predicts that the strong coupling strength $\as$ decreases with increasing energy or momentum transfer ...
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Embedment strength of dowels in wood specimens according to ABNT NBR 7190 (1997) and EUROCODE 5 (2004)

open access: yesREM: International Engineering Journal
The study of connections for timber structures has been the subject of intense research in Brazil. This work aimed to study the embedment strength of connections made by steel pins (dowels) in specimens of reforested woods.
Julio Cesar Molina   +3 more
doaj   +1 more source

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