Results 221 to 230 of about 514,337 (251)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Thermoelectric Detection of Crossed Andreev Reflections in Quantum Hall/Superconductor Hybrid Structures. [PDF]

Nat Commun
Wang J, Ahadi S, Liu B, Balents L, Munyan S, Stemmer S.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Dissemination of evidence-based homeopathy before Brazilian medical institutions as a strategy to strengthen the homeopathic medical specialty. [PDF]

Clinics (Sao Paulo)
Teixeira MZ.
europepmc   +1 more source

The effect of student-led healthcare career experience activity on nursing students' professional commitment: Study protocol for a randomized cross-over trial. [PDF]

PLoS One
Yang S, Lv Y, Yu B, Chen W, Peng J, Mohamad MA.   +5 more
europepmc   +1 more source

The brain age gap as a predictor of alcohol initiation in adolescence. [PDF]

Dev Cogn Neurosci
Byrne H, Visontay R, Devine EK, Wade NE, Jacobus J, Moore AJ, Squeglia LM, Mewton L.   +7 more
europepmc   +1 more source

The Augmented Leader: Four Competencies for AI-Integrated Leadership Development in Higher Education. [PDF]

New Dir Stud Leadersh
Lopez-Lopez D, Garcia PR, Garcia MS, Marco-Simó JM.   +3 more
europepmc   +1 more source

AI-Enabled Hardware-in-the-Loop Validation for Automotive Cybersecurity: A Review of Cyber Threats, Testbeds, and Intelligent Detection. [PDF]

Sensors (Basel)
Kordi F, Fortier P, Miled A.
europepmc   +1 more source

Can Laws Be Flexible? Rethinking Legislation for Innovation. [PDF]

NPJ Digit Med
Schneider NK, Stern AD, Price Ii WN, Lennerz JK.   +3 more
europepmc   +1 more source