Results 121 to 130 of about 1,398,079 (317)
Expert Talk given at "Crafting Europe"
https://www.craftingeurope.com/expert-talks/silvia-weidenbach-expert-talks ...
Weidenbach, Silvia
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
A Rule-based CBR Approach for Expert Finding and Problem Diagnosis,
, 2012 [[abstract]]It is important to find the person with right expertise and the appropriate solutions in the specific field to solve a critical situation in a large complex system such as an enterprise level application.
曾憲雄;Tseng, Shian-Shyong;廖岳祥;Anthony, Y.H.Liao +1 more
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Prolog and expert systems [PDF]
, 1987 The first part of the thesis provides an introduction to the logic programming language Prolog and some areas of current research. The use of compilation to make Prolog faster and more efficient is studied and a modified representation for complex ...
Davies, Peter Leslie
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Expert systems and the emergence of teledesign
, 2001 This paper considers the extent to which the amateur use of expert systems for home design challenges traditional views of the design process. The issues are examined in the context of competing definitions of design.
Crabbe, A
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
BAYESIAN STRATEGY FOR GROUP DECISION MAKING AND ITS INTERVAL GENERALIZATION
Міжнародний науково-технічний журнал "Проблеми керування та інформатики"An original approach to formalize the process of group decision making based on the integration of private decisions of independent experts is developed.
О.А. Жуковська +1 more
doaj +1 more source
Designing an Estimation Pattern for Reliability of Launch Vehicle Structure with Bayesian Networks [PDF]
فصلنامه علوم و فناوری فضایی, 2012 Failures identification of vital and sensitive products and their reliability estimation, before applying affects design improvement of them. On the other hand, because of lack of data,reliability estimation of some systems such asspace products is hard ...
S. M. M. Sharifi +3 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source