Results 41 to 50 of about 1,662,238 (307)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
СибСкриптThe article features the role of expert approaches in decision-making concerning the military intervention in Afghanistan by the USSR and the USA. The author identified the subjects, methods, and functions of political expertise in the war in Afghanistan
V. V. Mironov
doaj +1 more source
The effectiveness of mHealth interventions for maternal, newborn and child health in low- and middle-income countries:Protocol for a systematic review and meta-analysis [PDF]
, 2014 Rates of maternal, newborn and child (MNCH) mortality and morbidity are vastly greater in low– than in high–income countries and represent a major source of global health inequity.
Begg +18 more
core +7 more sources
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Implementation of Community Policing Strategy: Impact of Community Factors in Nairobi Country [PDF]
, 2019 Crime is a community problem and not just a police problem. The adoption and implementation of Community Policing (CP) in the 1980s, was perceived as departure from the professional ‘police-as- expert’ model of public safety that had been dominant for a ...
Kabage, Robert Gichangi
core
Expert Detection In Question Answer Communities
International Journal of Web Research, 2022 Community Question Answering has a crucial role in almost all societies nowadays. It is important for the owners of a community to be able to make it better and more reliable. One way to achieve this, is to find the users who have more knowledge, expertise, experience and skill and can well share their knowledge with others (which we call experts and ...
Salimian, Hamed +2 more
openaire +2 more sources
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
RUDN journal of SociologyToday informatization and digitalization are the only viable megatrend for innovative social transformation; however, the rapid development and global spread of digital information and communication technologies (ICT) have led to complex, multifaceted ...
V. Yu. Dunaev +3 more
doaj +1 more source
PROFESSIONAL COMMUNICATION AND LANGUAGE EXPERTS
, 2021 This paper aims to develop a model of a potential syllabus to be used for the academic subject Professional Communication (in English) taught to second-year students in Applied Modern Languages, starting from the premise that they may become good communicators in areas that go beyond their domain.
openaire +1 more source
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source