Results 131 to 140 of about 203,481 (279)

Expert Consensus Methods In The Humanities: An Exploration of their Potential [version 2; peer review: 2 approved, 1 approved with reservations]

F1000Research
Background Despite the significant role of consensus and dissensus in knowledge production, formal approaches to consensus are notably less common in the humanities compared to their frequent application in natural, social, and life sciences.
Lex Bouter, Tamarinde Haven, Lidwine B. Mokkink, Rik Peels, Charlotte C.S. Rulkens   +4 more
doaj  

Clinical features and outcomes of carotid artery stenting by clinical expert consensus criteria: A report from the CARE registry [PDF]

, 2009
H. Vernon Anderson, Kenneth A. Rosenfield, Christopher J. White, Kalon K.L. Ho, John A. Spertus, Philip G. Jones, Fengming Tang, Christopher U. Cates, Michael R. Jaff, Walter J. Koroshetz, Irene Katzan, L. Nelson Hopkins, John S. Rumsfeld, Ralph G. Brindis   +13 more
openalex   +1 more source

LncDARS‐AS1 Regulates ATP1A1 Stability and Enhances Na+/K+ ATPase Activity to Promote Osteosarcoma Metastasis

Advanced Science, EarlyView.
This study identifies LncDARS‐AS1 as a novel oncogenic regulator that stabilizes ATP1A1 and enhances Na⁺/K⁺ ATPase activity, promoting osteosarcoma metastasis. Targeting the LncDARS‐AS1/ATP1A1/NKA axis, including pharmacological inhibition with digoxin, offers promising opportunities for the development of new therapeutic strategies against ...
Mingxian Xu, Jiatian Wei, Xiaoyu Feng, Qinkai Zhang, Jian Chen, Xinyue Wang, Xiudan Zhan, Bing Lu, Weitang Guo, Mingzhe Cheng, Renxuan Huang, Shao Xu, Changye Zou   +12 more
wiley   +1 more source

Polyanalgesic consensus conference 2003: an update on the management of pain by intraspinal drug delivery— report of an expert panel

, 2004
Samuel J. Hassenbusch, Russell K. Portenoy, Michael J. Cousins, Eric Buchser, Timothy R. Deer, Stuart L. Du Pen, James C. Eisenach, Kenneth A. Follett, Keith R. Hildebrand, Elliot S. Krames, Robert M. Levy, Pamela Pierce Palmer, James P. Rathmell, Richard Rauck, Peter S. Staats, Lisa Stearns, K. Dean Willis   +16 more
openalex   +1 more source

HPD is an RNA‐Binding Protein Sustaining Ovarian Cancer Cell Glycolysis, Tumor Growth, and Drug Resistance

Advanced Science, EarlyView.
HPD is identified as an RNA‐binding protein that promotes mRNA translation by binding to RRACH motifs via its double‐stranded RNA‐binding domains. This RNA‐binding activity critically sustains glycolysis in ovarian cancer cells. Disrupting HPD's RNA‐binding function effectively suppresses tumor growth and enhances therapeutic sensitivity, highlighting ...
Fei Xie, Han Zhang, Xintong Dai, Mengxin Tu, Chenxi Yu, Lumeng Liu, Yajuan Guo, Huanran Sun, Qingle Gao, Jiyan Wang, Mingming Sun, Qijun Zhang, Taoyuan Wang, Tao He, Zhen Li, Yanping Li, Tao Wang, Jianguo Zhao, Zhongjie Chen, Chunze Zhang, Shuai Zhang, Changliang Shan   +21 more
wiley   +1 more source

AntiBMPNN: Structure‐Guided Graph Neural Networks for Precision Antibody Engineering

Advanced Science, EarlyView.
AntiBMPNN, a deep learning framework that integrates antibody‐specific 3D data, MPNN, frequency‐based scoring, and AlphaFold 3, achieves superior antibody sequence design. In most cases, it outperforms ProteinMPNN, AntiFold, and AbMPNN in CDR design, demonstrating higher binding affinities and sequence recovery.
Ze‐Yu Sun, Jiayi Yuan, Divya Jaiswal, Jingxuan Ge, Tianjian Liang, Jiahui Wei, Jinghong Cao, Yulong Li, Xiaojie Chu, Yan Chen, Ying Xue, Wei Li, Tingjun Hou, Zhiwei Feng   +13 more
wiley   +1 more source

European Myeloma Network: the 3rd Trialist Forum Consensus Statement from the European experts meeting on multiple myeloma [PDF]

, 2010
Monika Engelhardt, Josefina Udi, Martina Kleber, Andrew Spencer, Alberto Rocci, Stefan Knop, Benedetto Bruno, Sara Bringhen, José Antonio Pérez‐Simón, Sonja Zweegman, Christoph Driessen, Francesca Patriarca, Martin Gramatzki, Evangelos Terpos, Orhan Sezer, Martin Kropff, Christian Straka, Hans Erik Johnsen, Anders Waage, Martin Boegsted, Henk M. Lokhorst, Roman Hájek, Gareth J. Morgan, Mario Boccadoro, Heinz Ludwig, Michèle Cavo, Aaron Polliack, Pieter Sonneveld, Hermann Einsele, Antonio Palumbo   +29 more
openalex   +1 more source

Integrating Molecular Dynamics and Machine Learning for Solvation‐Guided Electrolyte Optimization in Lithium Metal Batteries

Advanced Science, EarlyView.
A data‐driven workflow integrating molecular dynamics simulations and machine learning enables efficient discovery of optimized lithium battery electrolytes. Key structural descriptors are screened for predicting coordination behavior and ion transport. Gaussian process regression identifies an optimal feature space, guiding rational electrolyte design.
Xiwang Chang, Yang Yang, Weiheng Xu, Zhe Wang, Wenhan Li, Hongda Gao, Dubin Huang, Aijun Li, Yaofeng Zhu   +8 more
wiley   +1 more source

Expert Consensus on Characteristics of Wisdom: A Delphi Method Study [PDF]

, 2010
Dilip V. Jeste, Monika Ardelt, Dan G. Blazer, Helena C. Kraemer, George E. Vaillant, T. W. Meeks   +5 more
openalex   +1 more source

Subgenome Partitioning and Polyploid Genome Evolution in the Loach Family Botiidae (Order Cypriniformes)

Advanced Science, EarlyView.
This study investigates subgenome evolution and polyploidy in Cypriniformes fish, revealing complex phylogenetic relationships and genomic dynamics. By applying advanced subgenome partitioning methods, it uncovers novel insights into transposon activity and gene fractionation.
Yunyun Lv, Jia Li, Yanping Li, Yu Huang, Qiang Lai, Zhengyong Wen, Jun Wang, Yang He, Jinrong Shi, Zejin Huang, Ying Jiang, Yves Van de Peer, Qiong Shi, Biwen Xie, Yongming Wang   +14 more
wiley   +1 more source