Results 81 to 90 of about 6,108,453 (204)
The rational thinking of expert opinion and communicating in courtroom
Journal of Forensic Science and Medicine, 2017 Since the past half century, expert testimony has played an increasingly important role in Chinese litigation. As the amount of expert testimony has grown, the issues about its admissibility and scientific foundation related to evidence are becoming to ...
Bing Li, Yuanfeng Wang
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2017 Final report appendices E-H of the Commission on Evidence-Based Policymaking (CEP) containing the information gathered through the commission's survey of federal offices, public meeting materials and presentations, public input-hearing testimony and ...
United States. Commission on Evidence-Based Policymaking
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Promise of Evidence-Based Policymaking, Final Report and Appendices A-D
, 2017 Final report of the Commission on Evidence-Based Policymaking (CEP) describing their activities and findings regarding evidence access, privacy protections, accountability, and building capacity.
United States. Commission on Evidence-Based Policymaking
core
18. Experts and expert evidence
, 2017 This chapter focuses on the role of experts in civil actions. It considers when expert support is needed — whether as part of the evidence submitted in the action, or as part of the advice sought to prepare the client’s case, or perhaps for both ...
Susan Cunningham-Hill, Karen Elder
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The new Wigmore ::a treatise on evidence : expert evidence /
, 2021 "A practical guide to the law of evidence, specifically as it relates to expert and scientific evidence. Audience: Any attorney practicing law in the United States"-
Kaye, D. H. +6 more
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