Results 101 to 110 of about 2,129,822 (303)

Expert evidence and the courts: 1. The history of expert evidence [PDF]

open access: yesAdvances in Psychiatric Treatment, 1999
Recommendations by Lord Woolf for the reform of the civil justice system in England and Wales include proposals which are already beginning to influence the provision of expert evidence to the courts. Lord Woolf has himself been instrumental in the establishment of an Expert Witness Institute which has caused some controversy in medical circles.
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Construction of evidence⁃based practice program for oral care in patients with cognitive impairment

open access: yesHuli yanjiu, 2022
ObjectiveTo construct an evidence⁃based practice program for oral care in patients with cognitive impairment.MethodsThe initial draft of evidence⁃based practice program for oral care in patients with cognitive impairment was formed through evidence ...
CAO Junyan, QIAO Jiange, YANG Qingmin
doaj  

Development of a Randomised Controlled Trial of Counselling for Depression [PDF]

open access: yes, 2011
Many members of the UK counselling community feel that their profession and practice is under threat, particularly within NHS settings. This can be attributed, primarily, to the near-complete absence of recommendations for counselling in clinical ...
Cooper, Mick
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The rational thinking of expert opinion and communicating in courtroom

open access: yesJournal of Forensic Science and Medicine, 2017
Since the past half century, expert testimony has played an increasingly important role in Chinese litigation. As the amount of expert testimony has grown, the issues about its admissibility and scientific foundation related to evidence are becoming to ...
Bing Li, Yuanfeng Wang
doaj   +1 more source

Formalism and judgement in assurance cases [PDF]

open access: yes, 2004
This position paper deals with the tension between the desire for sound and auditable assurance cases and the current ubiquitous reliance on expert judgement.
Strigini, L.
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Expert evidence: The new rules [PDF]

open access: yes, 2008
This paper considers the nature of expert evidence before turning to the criticisms made and reforms suggested by the Chief Justice’s Working Party on Civil Justice Reform (“CJR”) insofar as they concern its use in the Hong Kong civil courts.
Meggitt, G
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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