Results 131 to 140 of about 5,111,330 (297)
Background The use of Expert Opinion (EO) in clinical guidelines is highly variable and lacks standardization, leading to ongoing controversy. A clear and universally accepted definition of EO is also lacking.
Blin Nagavci +2 more
doaj +1 more source
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Evidence into recommendations: How expert groups formulate clinical guidelines
This report outlined the findings of the Evidence into Recommendations study, identifying the key influences on decision making in the formulation of clinical guidelines.
McAteer, J. +3 more
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CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Evidence summary: COVID-19 - physiotherapy rehabilitation [v2.0]
A team of expert researchers and clinicians within the intensive care and acute cardiorespiratory fields have collaborated to produce: Physiotherapy management for COVID-19 in the acute hospital setting: recommendations to guide clinical practice1. These
National Health Library and Knowledge Service Evidence Team
core
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Criminal profiling as expert evidence
This chapter looks at profiling as expert evidence. While not allowed in many jurisdictions, others have been more receptive to this type of expert testimony.
Petherick, Wayne +7 more
core +1 more source
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Objectification of injuries and consequences in expert medical opinions
Background: Only unequivocal evidence confirming the total extent of injury. Biomechanical analysis, objectifications of permanent consequences after injury and objectification, whether such injuries influence life activities of an injured person, should
Miran Vrabl
doaj
Summary Document: Evidence Sources for Mildly Symptomatic COVID-19 Treated in a Non-Hospital Setting
The following information resources have been selected by the National Health Library and Knowledge Service Evidence Virtual Team in response to a request to collate the best available evidence and guidance pertaining to asymptomatic or mildly ...
National Health Library and Knowledge Service Evidence Team
core

