Results 101 to 110 of about 6,108,453 (204)

The Promise of Evidence-Based Policymaking: Appendices E-H

open access: yes, 2017
Supplementary appendices that support the final report of the Commission on Evidence-Based Policymaking including ..
United States. Commission on Evidence-Based Policymaking.
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Promise of Evidence-Based Policymaking

open access: yes, 2017
Report of the Commission on Evidence-Based Policymaking providing a final report of their findings that..
United States. Commission on Evidence-Based Policymaking.
core  

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

Pre-Trial Management of Expert Evidence in the Kilmore East Bushfire Proceeding

open access: yes, 2016
This paper, the first in a series on the management of expert evidence during the Kilmore East bushfire proceeding, considers the pre-trial management of experts.
McKenzie, Simon
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Reconsidering the Admissibility of Expert Forensic Evidence in South African Criminal Proceedings

open access: yesPotchefstroom Electronic Law Journal
Expert forensic evidence can be of great assistance in criminal proceedings. However, the question that must be answered is whether and to what extent there is science in any forensic science discipline.
Chevaure Du Pokoy
doaj   +1 more source

Expert Evidence Reliability

open access: yes, 2014
This article considers the Government's response to the Law Commisison's proposals on Expert Evidence in Criminal Proceedings in England and Wales and recent developments in the family (expert standards)and civil (hot-tubbing ...
Stockdale, Michael, Wilson, Tim
core  

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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