Results 141 to 150 of about 526,778 (254)

Digital Competence in Managing Digital Resources Among Health Professions Faculty in Ethiopian Public Universities: Implications for CME/CPD Digital Transformation. [PDF]

J CME
Equlinet Misganaw A, Giletew Wondie A.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Delphi Study on the Development of a Traditional Chinese Medicine Syndrome-Differentiation Nursing Framework for Patients with Cirrhotic Ascites. [PDF]

J Multidiscip Healthc
Huang S, Zhang L, Yang S, Zheng F, Tan S, Huang D.   +5 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Diagnosis and management of Children with Post-Intensive Care Syndrome in Paediatrics: Clinical Practice Guidelines by the French National Authority for Health (HAS). [PDF]

Ann Intensive Care
Chareyre J, Pouletty M, Morin L, Sebaiti MA, Brosolo J, Berthaud C, Chevé A, Deneux V, Eches L, Genet C, Kolev K, Lejeune A, Ricignuolo C, Rossi JC, Tiberghien D, Micaelli D, Mainguy A, Levy M, French PICS-p study group.   +18 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Evidence-based perioperative nutritional management for patients undergoing prostate cancer surgery: a systematic review. [PDF]

Gland Surg
Mao Y, Chen T, Chen J, Luo M, Wu Q, Zhu J, Chen Y.   +6 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Infant gut microbiota following cesarean section in the Middle East: a multidisciplinary expert consensus based on a targeted narrative review. [PDF]

Front Pediatr
Aldekhail W, Al-Beltagi M, Indrio F, Al-Nemri AM, Tomerak A, Al Sawai A, Al-Refaee F, Al-Ghanem G, Rozi IH, Alallah J, Khan JM, Abouhazima K, Al-Mannaei K, El-Atawi K, Sleiman R, Miqdady M.   +15 more
europepmc   +1 more source