Results 91 to 100 of about 6,108,453 (204)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Criminal profiling as expert evidence
, 2014 This chapter looks at profiling as expert evidence. While not allowed in many jurisdictions, others have been more receptive to this type of expert testimony.
Petherick, Wayne +7 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Research Integrity and Peer ReviewExperts and their opinions can play a pivotal role in research for decision-making, particularly where empirical data are limited or uncertain. However, the methods by which expert input is solicited, synthesised, and applied in research often lack ...
Lesley Uttley +4 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Surveillance cameras, identification and expert evidence [PDF]
, 2014 Tony Ward discusses the use of expert evidence in comparing digital images derived from surveillance camera photographs with facial images of a suspect, arguing that while such evidence has serious limitations, the courts are right to admit it, but they ...
Ward, Tony
core +1 more source
, 2019 Expert Evidence: Law, Practice, Procedure and Advocacy, now in its Sixth Edition, is the acclaimed work of first resort for analysing the complex law and practice surrounding expert witnesses and expert evidence in personal injury, commercial, criminal ...
Powell, Martine +2 more
core
The Reliable Application of Fingerprint Evidence [PDF]
, 2018 In November 2017, a state appellate court did something almost unprecedented: It held that a trial judge made an error by admitting testimony on latent fingerprinting. In State v.
Garrett, Brandon L., Garrett, Brandon
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source