Results 141 to 150 of about 525,770 (217)

Challenges to court room mental health decision-making in the face of uncertainty. [PDF]

Front Psychiatry
Duggan C, Sarkar J.
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Development of Evidence-based Recommendations: Implications for Preparing Expert Consensus Statements

Chinese Medical Journal, 2016
Joey S W Kwong, Hao Chen, Xin Sun
doaj   +1 more source

Modulate Obesity and relateD metabolic complIcations For Yielding improvements in IBD outcomes (MODIFY-IBD): consensus on obesity and cardiometabolic comorbidities in inflammatory bowel disease using systematic reviews and the RAND/UCLA appropriateness method. [PDF]

BMJ Open
Devi J, Samaan S, Sehgal P, Mohamed M, Vincent M, Coombs S, Doering M, Barnes EL, Johnson AM, Yarur AJ, Deepak P.   +10 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A temporally Anchored Retrieval-Augmented Generation Framework for Metabolic and Bariatric Surgery Patient Education: An IFSO Artificial Intelligence Task Force Multinational Validation Study. [PDF]

Obes Surg
Atri YK, Hartvigsen T, Lee Y, Okrainec A, Kermansaravi M, Shahabi S, Leite S, O'Kane M, Cohen R, Shin TH.   +9 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

An evidence-based nursing management app prototype for adult urology day surgery: an AI-driven development pathway. [PDF]

BMC Nurs
Fang Q, Zhao Y, Lai M, Hu G, Li M, Zhou X, Rao Y, Ma X.   +7 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

ASO Author Reflections: From Recommendation to Reality: Expert Multidisciplinary Collaboration in Intrahepatic Cholangiocarcinoma Care. [PDF]

Ann Surg Oncol
Zwaan TC, Buettner S, Groot Koerkamp B, Olthof PB, Dutch Hepatocellular and Cholangiocarcinoma Group.   +4 more
europepmc   +1 more source