Results 81 to 90 of about 579,829 (295)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Re-Thinking Expert Evidence

, 2019
The jurisprudence surrounding expert evidence in Canadian law has evolved since the 1994 case, R. v. Mohan, but it is still replete with numerous problems.
Freedman, Joshua A.M.
core   +2 more sources

Electronic legal databases

, 2007
Electronic Legal Databases in Expert evidence edited by Ian Freckelton and Hugh Selby. Sydney, LBC Information Services.
NAUMCZYK, Elizabeth Barbara
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Using Pretest-Posttest Research Designs to Enhance Jury Decision-Making

Oñati Socio-Legal Series, 2015
When lay jurors are unfamiliar with key evidentiary issues, expert evidence, judicial instructions and group deliberation may enhance their understanding of this evidence.
Jane Goodman-Delahunty, Natalie Martschuk, Anne Cossins   +2 more
doaj  

The Admissibility of Scientific Expert Evidence Under Indonesian Criminal Justice System

Sriwijaya Law Review, 2019
In many cases, such as corruption and forestry-related crimes, an expert has a significant role in explaining the impact of the crime. For instance, scientific expert evidence is required to disclose about the ecological destruction that occurred due to ...
Wanodyo Sulistyani
doaj   +1 more source

What makes an expert persuasive? Examining the influence of evidence quality and superficial cues on jurors' evaluation of expert evidence

, 2023
Expert evidence offers important aid in legal trials, and often lay jurors must decide how much weight the expert opinion ought to be given when making consequential decisions (e.g., whether a defendant is implicated in a crime).
Younan, Mariam ; https://orcid.org/
core   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Expert evidence in criminal procedures [PDF]

, 2017
In het Nederlandse strafproces wordt regelmatig gebruik gemaakt van deskundigenbewijs. De inzet van deskundigen in strafzaken is echter niet vanzelfsprekend.
Hoving, Roelf Anton; id_orcid
core   +4 more sources

A transparent approach: Openness in forensic science reporting

Forensic Science International: Synergy
There have been numerous calls for increased transparency and disclosure in forensic science. However, there is a paucity of guidance on how to achieve this transparency in reports, and the impacts it may have on criminal justice proceedings. We describe
Kaye N. Ballantyne, Stephanie Summersby, James R. Pearson, Katherine Nicol, Erin Pirie, Catherine Quinn, Rebecca Kogios   +6 more
doaj   +1 more source