Results 51 to 60 of about 872,862 (290)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Semi-parametric analysis of multi-rater data [PDF]

open access: yes, 2009
Datasets that are subjectively labeled by a number of experts are becoming more common in tasks such as biological text annotation where class definitions are necessarily somewhat subjective.
Girolami, M., Polajnar, T., Rogers, S.
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Kilka refleksji na kanwie rozważań zamieszczonych w książce pt. Pozycja biegłego w polskim systemie prawnym, pod red. B. Lewandowskiego, Warszawa 2016

open access: yesActa Iuris Stetinensis, 2017
The article presents a few reflections on the expert opinion in the Polish criminal process. The article describes some general problems related to the expert’s opinion including the question of the specifics of the expert’s opinion in comparison to ...
Małgorzata Żbikowska
doaj   +1 more source

Landscape character in the expert opinions typology of forensic ecotechnique: forest and trees [PDF]

open access: yes, 2014
The paper deals with the issue of landscape character within the expert opinions typology of Forensic ecotechnique: forest and trees. Expert opinions regarding landscape character are classified according to the character of task.
Honzová, Markéta
core  

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

Analysis reuse exploiting taxonomical information and belief assignment in industrial problem solving [PDF]

open access: yes, 2013
To take into account the experience feedback on solving complex problems in business is deemed as a way to improve the quality of products and processes. Only a few academic works, however, are concerned with the representation and the instrumentation of
Al-Mubaid   +42 more
core   +2 more sources

Expert opinion process

open access: yesProceedings of the 10th International Conference on Education Technology and Computers, 2018
Expert opinion is a technique used in different areas of scientific research, which, in some way, guarantees its social and methodological validity. This method is also used as an instrument to make long-term predictions, with different types of solutions to obtain a concise answer that is achieved with the help of experts who exchange information ...
Bayona-Ore, Luz   +2 more
openaire   +2 more sources

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

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