Results 171 to 180 of about 696,114 (317)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Can a Rule-Based Expert System Diagnose Nasal Obstruction from Nasoendoscopy Videos? [PDF]

open access: yesFacial Plast Surg
Navaratnam A   +5 more
europepmc   +1 more source

Computer-aided diagnosis of primary membranous nephropathy using expert system. [PDF]

open access: yesBiomed Eng Online, 2023
Gao J   +6 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

IoT Based Expert System for Diabetes Diagnosis and Insulin Dosage Calculation. [PDF]

open access: yesHealthcare (Basel), 2022
Valsalan P   +4 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

An Ontology-Based Expert System Approach for Hearing Aid Fitting in a Chaotic Environment. [PDF]

open access: yesAudiol Res
Ngounou GM   +4 more
europepmc   +1 more source

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