Results 61 to 70 of about 2,706,996 (304)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The Feasibility of Using Expert Systems in the Management of Human Resources [PDF]

open access: yes, 1990
The purpose of this paper is to introduce a decision aid that is being used increasingly in the business world, the expert system, and to begin to examine its potential for human resource management.
Hannon, John M.   +2 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

"ELECTRONIC EXPERT" EXPERT SYSTEM SUBSYSTEM'S "DE- SIGN" CONSTRUCTION FEATURES

open access: yesВестник Донского государственного технического университета, 2018
One of the expert system for maintenance service of combine harvester subsystem's structure will be carried out.
L.V. BORISOVA
doaj  

Marine Navigation Using Expert System [PDF]

open access: yesTransNav, 2009
A ship's autopilot adjustment is a matter of utmost importance since it affects its safety, command as well as fuel and time efficiency. A number of methods have been developed in order to cope with this issue usually based on models that simulate the ...
Nikitas Nikitakos, George Fikaris
doaj  

Equating an expert system to a classifier in order to evaluate the expert system [PDF]

open access: yes
A strategy to evaluate an expert system is formulated. The strategy proposed is based on finding an equivalent classifier to an expert system and evaluate that classifier with respect to an optimal classifier, a Bayes classifier.
Odell, Patrick L.
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

"ELECTRONIC EXPERT" EXPERT SYSTEM SUBSYSTEM'S "DE- SIGN" CONSTRUCTION FEATURES

open access: yesAdvanced Engineering Research, 2009
One of the expert system for maintenance service of combine harvester subsystem's structure will be carried out.
L.V. BORISOVA
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

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