Results 31 to 40 of about 25,120,416 (357)

Infoscience technology: the impact of internet accessible melanoid data on health issues

open access: yesData Science Journal, 2006
In this paper the development of a new internet information system for analyzing and classifying melanocytic dat, is briefly described. This system also has some teaching functions, improves the analysis of datasets based on calculating the values of the
J W Grzymała-Busse   +3 more
doaj   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Agricultural expert systems are a source of information

open access: yesCybrarians Journal, 2007
This article discusses the use and usefulness of Agricultural Expert Systems as information source, Those Expert Systems as very important supporting tools for helping people in the decision making process, also this article discusses the role of Central
Amany Ramadan
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Prompt-Driven and Kubernetes Error Report-Aware Container Orchestration

open access: yesFuture Internet
Background: Container orchestration systems like Kubernetes rely heavily on declarative manifest files, which serve as orchestration blueprints.
Niklas Beuter   +2 more
doaj   +1 more source

Applications of Expert Systems in Transport [PDF]

open access: yes, 1986
BACKGROUND Experienced judgement and specialist knowledge are essential to the proper specification, understanding and interpretation of data and computer analyses.
Bonsall, P.W., Kirby, H.R., Kwan, R.S.
core  

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Complex systems science: expert consultation report [PDF]

open access: yes, 2009
Executive SummaryA new programme of research in Complex Systems Science must be initiated by FETThe science of complex systems (CS) is essential to establish rigorous scientific principles on which to develop the future ICT systems that are critical to ...
Bourgine, Paul   +2 more
core  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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