Results 31 to 40 of about 1,035,590 (321)

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Choose qualified instructor for university based on rule-based weighted expert system [PDF]

arXiv, 2022
Near the entire university faculty directors must select some qualified professors for respected courses in each academic semester. In this sense, factors such as teaching experience, academic training, competition, etc. are considered. This work is usually done by experts, such as faculty directors, which is time consuming.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

Evaluation of a Bi-Directional Methodology for Automated Assessment of Compliance to Continuous Application of Clinical Guidelines, in the Type 2 Diabetes-Management Domain [PDF]

arXiv, 2021
We evaluated the DiscovErr system, in which we had previously implemented a new methodology for assessment of compliance to continuous application of evidence-based clinical guidelines, based on a bidirectional search from the guideline objectives to the patient's longitudinal data, and vice versa.
arxiv  

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Evaluation of Artificial Intelligence Effectiveness in Detection of Lumbosacral Spine Degenerative Diseases

Вестник рентгенологии и радиологии
Objective: comparative evaluation of output data of a set of trained convolutional neural network (CNN) models and interpretation of pathological changes in lumbar spine by radiologists during magnetic resonance imaging.Material and methods. More than 12,
N. В. Nudnov, A. V. Korobov, А. А. Skachkov, T. V. Kulneva, V. V. Sherstoboev, L. А. Titova, A. S. Rusakov, V. V. Tumko, R. S. Sarbaev, N. А. Uspenskaya, E. А. Andrienko, M. Е. Ivannikov   +11 more
doaj   +1 more source

SSR-TA: Sequence to Sequence based expert recurrent recommendation for ticket automation [PDF]

arXiv, 2023
The ticket automation provides crucial support for the normal operation of IT software systems. An essential task of ticket automation is to assign experts to solve upcoming tickets. However, facing thousands of tickets, inappropriate assignments will make tickets transfer frequently among experts, which causes time delays and wasted resources ...
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Evaluating Preprocessing Techniques for Unsupervised Mode Detection in Irish Traditional Music

Applied Sciences
Significant computational research has been dedicated to automatic key and mode detection in Western tonal music, particularly within the major and minor modes.
Juan José Navarro-Cáceres, Diego M. Jiménez-Bravo, María Navarro-Cáceres   +2 more
doaj   +1 more source