Results 111 to 120 of about 29,796 (251)

Real‐World, Prospective, Multicenter Outcomes to Brodalumab Treatment in Patients With Moderate‐to‐Severe Psoriasis in Greece (The RESOLVE Study)

open access: yesJEADV Clinical Practice, EarlyView.
RESOLVE was a prospective, real‐world study in patients with moderate‐to‐severe psoriasis treated with brodalumab. At Week 12, 76.4% achieved PASI ≤ 3, 53.5% PASI100, and 71.5%/54.2% achieved sPGA0/1 and sPGA 0, respectively. At Week 52, 96.1% achieved sPGA success (clear/almost clear). Furthermore, at Week 52, mean DLQI scores decreased by 12.6 ± 6.2,
Electra Nicolaidou   +10 more
wiley   +1 more source

Health‐Related Quality of Life in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis: A Qualitative Study

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters   +9 more
wiley   +1 more source

Overall Cumulative Burden of Hidradenitis Suppurativa: An In‐Depth Qualitative Examination

open access: yesJEADV Clinical Practice, EarlyView.
This qualitative study examined the cumulative burden of Hidradenitis Suppurativa (HS) through in‐depth cross‐sectional interviews with 40 patients. The thematic analysis revealed five major concepts: challenging choices, prevalent negative emotions (fear, anxiety, depression), companionship (social support/isolation), life being ‘on hold’ due to ...
Burhan A. Buttar   +13 more
wiley   +1 more source

The Bazaar as a Model for Knowledge Work

open access: yesKnowledge and Process Management, EarlyView.
ABSTRACT This paper presents fieldwork that extends existing metaphors of knowledge work as a process shaped by hierarchical or market forces. A qualitative, ethnographic study of six knowledge‐intensive businesses in two countries identifies striking parallels with the Middle Eastern bazaar in contrast to Western impersonal markets and hierarchies. We
Reed Elliot Nelson   +2 more
wiley   +1 more source

Complementary and Integrative Medicine for the Treatment of Tourette's Syndrome

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background There is widespread interest in complementary and integrative medicine (CIM) among people with Tourette's syndrome (TS). Objective To perform a systematic review of evidence on the use of CIM to reduce tics and improve tic‐related quality of life.
Tamara Pringsheim   +21 more
wiley   +1 more source

Big Data Technology Fusion Back Propagation Neural Network in Product Innovation Design Method

open access: yesIET Networks, Accepted Article., 2022
This research uses big data technology to combine the process of product innovation design method, which has certain significance for the formation of intelligent and systematic product innovation design method. Meanwhile, while predicting the results of all products innovative design methods, it can improve the product's predictive innovative design ...
Ren Li, Qiang Zeng
wiley   +1 more source

Considerations for Initiation and Maintenance of Foslevodopa/Foscarbidopa for Advanced Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background As Parkinson's disease (PD) progresses, motor fluctuations become increasingly difficult to manage with oral medications. Foslevodopa/foscarbidopa (LDp/CDp), delivered as a continuous 24‐h/day subcutaneous infusion, offers continuous levodopa delivery and stable plasma levodopa levels that reduce motor fluctuations. LDp/CDp has been
K. Ray Chaudhuri   +20 more
wiley   +1 more source

Legal governance countermeasures for social problems based on the clustering algorithm under the application of big data technology

open access: yesIET Networks, EarlyView., 2022
This work aims to improve the comprehensive role of big data technology in promoting social development and reduce the continuous emergence of social problems under the background of big data application. Abstract The purpose is to improve the security of the application of big data technology and ensure the stable development of society in the context
Xuejie Zhao
wiley   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier   +13 more
wiley   +1 more source

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