Results 151 to 160 of about 326,583 (330)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

INTERACTION BETWEEN LEGAL PROFESSIONALS AND FORENSIC EXPERT WITNESSES: PROBLEMS AND SOLUTIONS

open access: yesТеория и практика судебной экспертизы, 2014
The author uses case studies to illustrate various problems of interaction betweenindividual forensic examiners, forensic science organizations and judges at the stagesof preparation for the appointment of forensic examinations, as well as court ...
S. Smirnova
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

SERIAL EFFECTS OF EVIDENCE ON LEGAL DECISION-MAKING

open access: yesEuropean Journal of Psychology Applied to Legal Context, 2012
The order in which evidence is presented to a criminal court might influence the verdict. This study investigated the serial position effect in a judicial context.
Raluca Enescu, André Kuhn
doaj  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

El médico en procesos judiciales

open access: yesActa Médica Costarricense, 2008
La opinión del médico como perito es requerida comúnmente en los procesos judiciales como evidencia. Uno de los fundamentos más importantes de la efectividad de su labor es comprender el proceso y mantener una conducta ética.
Grettchen Flores-Sandí
doaj  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

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