Results 91 to 100 of about 2,699,909 (326)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

P1743: IDENTIFYING DUTCH HOSPITALIZED PATIENTS AT HEMATOLOGY WARDS WITH A LIMITED LIFE EXPECTANCY: A SUBGROUP ANALYSIS OF A FLASH MOB STUDY

open access: yesHemaSphere, 2022
A. van der Velden   +4 more
doaj   +1 more source

Expertise revisited I: Interactional Expertise

open access: yes, 2016
39 pages, one ...
Collins, Harry, Evans, Robert
openaire   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Construction durable : expertise et contre-expertise d’architectes

open access: yesVertigO, 2013
L’institutionnalisation du développement durable dans le domaine de l’architecture induit diverses transformations dans le recours à l’expertise, à propos desquelles les architectes arborent des positions hétérogènes. Certains d’entre eux constituent des supports aux évolutions des politiques publiques, et tendent dès lors à être considérés comme des ...
openaire   +4 more sources

Sherlock Holmes: An expert’s view of expertise [PDF]

open access: yes, 2007
In recent years, there has been an intense research effort to understand the cognitive processes and structures underlying expert behaviour. Work in different fields, including scientific domains, sports, games, and mnemonics, has shown that there are ...
Didierjean, A, Gobet, F
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Expertise and Service: A Call to Action [PDF]

open access: yes, 2014
Although theological librarianship occurs most often at seminaries or graduate level theology programs, there are also librarians working with theology on an undergraduate level.
Butler, Rebecca
core   +2 more sources

Collaborative assessment of information provider's reliability and expertise using subjective logic [PDF]

open access: yes, 2011
Q&A social media have gained a lot of attention during the recent years. People rely on these sites to obtain information due to a number of advantages they offer as compared to conventional sources of knowledge (e.g., asynchronous and convenient access).
Oleshchuk, V   +2 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

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