Results 241 to 250 of about 2,905,481 (303)

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura   +4 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

open access: yesAdvanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong   +4 more
wiley   +1 more source

Organizational management of moderate and severe paediatric traumatic brain injury: results from a European survey. [PDF]

open access: yesBrain Spine
Hornshøj Pedersen S   +8 more
europepmc   +1 more source

Curriculum Innovation: A Master Clinician Residency Track in Neurology. [PDF]

open access: yesNeurol Educ
Richie M   +3 more
europepmc   +1 more source

One-pot green synthesis, biological evaluation, and in silico study of pyrazole derivatives obtained from chalcones

open access: yesGreen Processing and Synthesis
Ghazaryan Emma   +8 more
doaj   +1 more source

Barriers and Opportunities to Include Underrepresented Population Groups in Vaccine Trials: Cross-Sectional, Observational, Online Survey Study From the VACCELERATE Research Network.

open access: yesJMIR Public Health Surveill
Tanriover MD   +14 more
europepmc   +1 more source

Perspectives on Clinical Champions Implementing Hospital-Based Opioid Treatment in US Hospitals.

open access: yesJAMA Netw Open
Peng L   +12 more
europepmc   +1 more source

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