Results 161 to 170 of about 60,361 (257)

The cost of explainability in artificial intelligence-enhanced electrocardiogram models. [PDF]

NPJ Digit Med
Patlatzoglou K, Pastika L, Barker J, Sieliwonczyk E, Khattak GR, Zeidaabadi B, Ribeiro AH, Ware JS, Peters NS, Ribeiro ALP, Kramer DB, Waks JW, Sau A, Ng FS.   +13 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A Hybrid Explainable AI Framework (HXAI) for Accurate and Interpretable Diagnosis of Alzheimer's Disease. [PDF]

Diagnostics (Basel)
Al-Bakri FH, Bejuri WMYW, Al-Andoli MN, Ikram RRR, Khor HM, Mispan MS, Yunos NM, Yusof NFA, Fauadi MHFM, Jaya ASM, Moketar NA, Yusop N, Burhanudin K, Marindah TP, Bustamin A, Zainuddin Z, Wahyuni D, Ariffin UK, The Alzheimer's Disease Neuroimaging Initiative.   +18 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A surgical approach to building impactful artificial intelligence. [PDF]

NPJ Digit Med
Williams SC, Khan DZ, Bano S, Blandford A, Clarkson MJ, Costanza E, Mazomenos EB, Stoyanov D, McCulloch P, Marcus HJ.   +9 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Early autism detection: a review of emerging technologies, biomarkers, and explainable AI approaches. [PDF]

Mol Brain
Agrawal R, Agrawal R.
europepmc   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Towards Explainable Multimodal Sensing for Swimming Analysis: Early Findings from the SWIM-360 Project. [PDF]

Sensors (Basel)
Camilleri V, Camilleri RY, Fialovszky M, Pace D, Seychell D, Montebello M.   +5 more
europepmc   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source