Results 251 to 260 of about 220,602 (307)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin, Hui‐An Lin, Sheng‐Feng Lin   +2 more
wiley   +1 more source

AI-Driven Mental Health Support for Caregivers of Individuals With Alzheimer Disease: Systematic Literature Review and Development of a Conceptual Framework.

JMIR Ment Health
Salma SU, Renduchintala CR, Siddique I, Sterling E, Sneha S, Sakib N.   +5 more
europepmc   +1 more source

HED-ID: an edge-deployable and explainable intrusion detection system optimized via metaheuristic learning. [PDF]

Sci Rep
Nasir K, Badri SK, Alghazzawi DM, Alghamdi MY, Alkhozae M, Almakky A, Alhazmi RM, Asghar MZ.   +7 more
europepmc   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

The cost of explainability in artificial intelligence-enhanced electrocardiogram models. [PDF]

NPJ Digit Med
Patlatzoglou K, Pastika L, Barker J, Sieliwonczyk E, Khattak GR, Zeidaabadi B, Ribeiro AH, Ware JS, Peters NS, Ribeiro ALP, Kramer DB, Waks JW, Sau A, Ng FS.   +13 more
europepmc   +1 more source

Explainability and Interpretability of Multilingual Large Language Models: A Survey

Association for Computational Linguistics 2025, Augenstein, Isabelle, Korhonen, Anna, Resck, Lucas   +3 more
openalex   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Ethical Responsibility in Medical AI: A Semi-Systematic Thematic Review and Multilevel Governance Model. [PDF]

Healthcare (Basel)
Martinho D, Sobreiro P, Domingues A, Martinho F, Nogueira N.   +4 more
europepmc   +1 more source

Random Task Assignment in YAWL Explained

Andreas V. Hense
openalex   +1 more source

Changes in Immune‐Inflammation Status and Acute Ischemic Stroke Prognosis in Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Inflammation is a critical risk factor for poor outcomes in cerebral infarction. Prior studies focused primarily on baseline inflammation status, neglecting dynamic longitudinal changes. We try to investigate the association between immune‐inflammation status alterations and stroke prognosis, and evaluated three systemic biomarkers'
Songfang Chen, Wenting Huang, Yitian Liu, Xuan Chen, Buyu Ke, Qian Shen, Hanyu Cai, Jing Sun, Yan Li, Yungang Cao, Beilei Hu, Keyang Chen   +11 more
wiley   +1 more source