Results 121 to 130 of about 1,180,576 (325)

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Synthetic Sentiment Cue Enhanced Graph Relation-Attention Network for Aspect-Level Sentiment Analysis

open access: yesIEEE Access
Aspect-level Sentiment Analysis (ASA) constitutes a critical task in natural language processing, aimed at detecting and classifying sentiment polarities associated with specific aspects in textual data.
Hongwei Tang, Haining Yan, Ran Song
doaj   +1 more source

TCP Congestion Control Identification [PDF]

open access: yes, 2014
Transmission Control Protocol (TCP) carries most of the traffic on the Internet these days. There are several implementations of TCP, and the most important difference among them is their mechanism for controlling congestion.
Ahmed, Mohammed
core  

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Explicit and Implicit Negation in the Natural Language

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2016
The article deals with the phenomenon of negation in language and speech. Their logic, psychologic and linguistic features are being discussed, as well as the functional aspect and stylistic potential of the phenomenon are under analysis.
Larisa N Lunkova
doaj  

Implementation of TAGE Method Using Seikkala Derivatives Applied to Two-Point Fuzzy Boundary Value Problems

open access: yesInternational Journal of Differential Equations, 2015
Iterative methods particularly the Two-Parameter Alternating Group Explicit (TAGE) methods are used to solve system of linear equations generated from the discretization of two-point fuzzy boundary value problems (FBVPs).
A. A. Dahalan, J. Sulaiman
doaj   +1 more source

The Construction of Curves and Surfaces Using Numerical Optimization Techniques [PDF]

open access: yes, 1985
Numerical optimization techniques are playing an increasing role in curve and surface construction. Often difficult problems in curve and surface construction, especially when some aspect of shape control is involved, can be phrased as a constrained ...
Ferguson, D. R.
core   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

Investigation of the three-dimensional flow field within a transonic fan rotor: Experiment and analysis [PDF]

open access: yes
An experimental investigation of the three dimensional flow field through a low aspect ratio, transonic, axial flow fan rotor has been conducted using an advanced laser anemometer (LA) system. Laser velocimeter measurements of the rotor flow field at the
Pierzga, M. J., Wood, J. R.
core   +1 more source

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