Results 131 to 140 of about 1,180,576 (325)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Explicit Aspect Annotation via Transfer and Active Learning

open access: yesProcedia Computer Science, 2023
Boudabous Maroua, Pappa Anna
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Measuring general sense of agency: a Japanese adaptation and validation of the sense of agency scale (J-SoAS)

open access: yesFrontiers in Psychology
The Sense of Agency (SoA) refers to the individual’s perception of control over actions and their subsequent impact on the external environment. SoA encompasses multiple dimensions, such as implicit/local and explicit/general, which can be quantitatively
Wenzhen Xu   +3 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

open access: yesFEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar   +3 more
wiley   +1 more source

Non-verbal sentences in Chadic

open access: yesStudies in African Languages and Cultures, 1992
The non-verbal sentences are sentences in which there is no explicit aspect marking and no verb. The predicate position of such sentences is usually filled by nouns, noun phrases, prepositional phrases or adverbials.
Nina Pawlak
doaj  

Aspect-Based Sentiment Analysis with Explicit Sentiment Augmentations [PDF]

open access: green, 2023
Jihong Ouyang   +5 more
openalex   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

open access: yesFEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner   +6 more
wiley   +1 more source

Ethics in Japanese business environment [PDF]

open access: yes
At first sight it is easy to understand that “ethics in business” is a field which aims at explaining problems of moral aspect which come up currently in the activity of economic agents from a market economy.
Caraiani Gheorghe, Maduţa Gyongyver
core  

Home - About - Disclaimer - Privacy