Results 161 to 170 of about 6,941,943 (289)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Explicit-in-time goal-oriented adaptivity

, 2019
Goal-oriented adaptivity is a powerful tool to accurately approximate physically relevant solution features for partial differential equations. In time dependent problems, we seek to represent the error in the quantity of interest as an integral over the
D. Pardo (23434450), E. Alberdi (23458231), Victor Calo (23286106), J. Muñoz-Matute (23495056), K. van der Zee (23495059)   +4 more
core  

AI use and risk disclosure by investment advisers. [PDF]

Front Artif Intell
Chincholikar S, Chawla R.
europepmc   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

The Form-based Development Plan: bridging the gap between theory and practice in urban morphology

, 2008
The format of local development plans and site-specific guidance tends to be based on land-use allocations rather than physical form. This approach has serious limitations, especially when dealing with urban design issues.
Hall, Anthony
core  

On the Structural Properties of Discrete-Time and Sampled-Data Hamiltonian Dynamics. [PDF]

Entropy (Basel)
Monaco S, Normand-Cyrot D.
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Opening the Window of the Mind: Do Large Language Models Possess Human-Like Visual Attention? [PDF]

J Intell
Jin H, Gui G, Wang Z, Cai Z, Tang Z, Zhang J, Wang J, Feng H.   +7 more
europepmc   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Linking Enol-Keto Tautomerization Ratios in β‑Diketones to Their Physical Properties Using Computational Quantum Chemistry. [PDF]

ACS Omega
Gabriel J, Na J, Guillermo B, Perez LJ, Hoy EP.   +4 more
europepmc   +1 more source