Results 71 to 80 of about 933,577 (262)

Deep-sea Fishery Resources Exploration in the Southeast Asian Waters

open access: yes, 2010
The project on “Deep-sea fishery resources exploration in the Southeast Asian Region” has been active since the 2007s with funding support from the Japanese Trust Fund. The overall objectives of the project are to collect information on deep-sea fishery

core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Coal measures superimposed gas reservoir and its exploration and development technology modes

open access: yes, 2022
Coal measures superimposed gas reservoir is a key reservoir type of coal-measure gas in coal bearing formation. The discovery, exploration and development practice of coal measures superimposed gas reservoirs in China have opened up a new chapter for the
Fuping, ZHAO   +6 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Is Youth Entrepreneurship a Necessity or an Opportunity?: A First Exploration of Household and New Enterprise Surveys in Latin America [PDF]

open access: yes, 2006
This paper highlights the importance of youth entrepreneurship in Latin America and the Caribbean, as well as the challenges and opportunities faced by young entrepreneurs.
Inter-American Development Bank
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Report of the Regional Workshop on the Standard Operation Procedure and Development/ Improvement of Sampling Gears for the Deep-Sea Resource Exploration, Samutprakan, Thailand

open access: yes, 2009
The Regional Workshop on the Standard Operating Procedure and Development/ Improvement of Sampling Gears for the Deep-Sea Resource Exploration was organized by the SEAFDEC Training Department in Thailand from 26 to 28 May 2009.
Southeast Asian Fisheries Development Center, Training Department
core  

The Development of Reference Sites for Mineral Exploration under Tec-Soc-Env Conditions

open access: yes, 2023
This paper introduces a framework of site selection to inform the optimal location of test sites in mineral exploration based on the three dimensions of technical, environmental and social factors. A novel two-stage procedure is introduced, consisting of
Gloaguen, R.   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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