Results 51 to 60 of about 10,775,671 (299)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Reservoir characterization and exploration potential of shale reservoir near denudation area: A case study of Ordovician–Silurian marine shale, China

Open Geosciences
The distribution of denudation areas has brought huge risks to the exploration and development of deep buried shale gas resources. The reservoir characterization and exploration potential near denudation areas is of great significance to the evaluation ...
Li Yuegang, Chen Weiming, Pu Junwei
doaj   +1 more source

Mesozoic and Cenozoic uplift–exhumation of the central Taihang Mountains and its influence on deposits preservation in the central North China Craton: apatite–zircon fission track thermochronology

All Earth
The Taihang Mountains are located in the central part of the North China Craton. The genesis of this mineralisation is closely associated with several Mesozoic plutons and coeval dykes.
Chang - Ping Li, Yuan Liu
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Exploring the Potential of Neuroproteomics in Alzheimer's Disease

Current Topics in Medicinal Chemistry, 2020
Alzheimer's disease (AD) is progressive brain amyloidosis that damages brain regions associated with memory, thinking, behavioral and social skills. Neuropathologically, AD is characterized by intraneuronal hyperphosphorylated tau inclusions as neurofibrillary tangles (NFTs), and buildup of extracellular amyloid-beta (Aβ) peptide as
Md. Sahab Uddin, Md. Tanvir Kabir, Md. Jakaria, Eduardo Sobarzo-Sánchez, George E. Barreto, Asma Perveen, Abdul Hafeez, May N. Bin-Jumah, Mohamed M. Abdel-Daim, Ghulam M. Ashraf   +9 more
openaire   +3 more sources

Feeding, Fear, and Acceptance: Caregivers’ Experiences of Nutritional Support During Childhood Cancer Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques, Mariana dos Santos Murra, Welinton Hirai, Ana Laura Balduino do Nascimento, Karla Emilia de Sá Rodrigues, Wilson Elias de Oliveira Junior   +5 more
wiley   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Methods for identifying system tasks of strategic management and improving efficiency of exploration enterprise

Горные науки и технологии, 2020
A geological exploration company is a modern enterprise, possessing advanced techniques and carrying out full range of high quality exploration for all types of solid minerals in accordance with world standards, which is the center of competence in ...
D. N. Moldashi
doaj   +1 more source

Representation of Sickle Cell Disease Patients in Pediatric and Adult Care: What We Discovered Using Informatics for Integrating Biology and the Bedside (i2b2) Data

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Transitioning from pediatric to adult care is a high‐risk period for individuals with sickle cell disease (SCD). An initial observation at one academic medical center suggested a sex‐based disparity in clinic populations, prompting a national investigation.
Laurie J. Duckworth, Kholod Alhassan, Ada De La Osa, John Stephen, Yue Yao, Diana J. Wilkie   +5 more
wiley   +1 more source