Results 101 to 110 of about 26,057,468 (299)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Social Media as a Mirror: Reflecting Mental Health Through Computational Linguistics
IEEE AccessThe world is grappling with a serious problem: many young individuals are taking their own lives. There is also a challenge in understanding the rising trend of this tendency.
Md. Iftekharul Mobin +4 more
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Química Nova, 2013 This study describes the use of Principal Component Analysis to evaluate the chemical composition of water produced from eight oil wells in three different production areas.
Fabiana Alves de Lima Ribeiro +6 more
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Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Statistical Analysis of Compression Methods for Storing Binary Image for Low-Memory Systems
Advances in Electrical and Electronic Engineering, 2013 The paper is focused on the statistical comparison of the selected compression methods which are used for compression of the binary images. The aim is to asses, which of presented compression method for low-memory system requires less number of bytes of ...
Roman Slaby, Jana Nowakova, Radim Hercik
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Climate change in NE Mexico: influence of the North Atlantic Oscillation
Investigaciones Geográficas, 2012 An exploratory analysis of temperature, precipitation and evaporation records, in five localities of Tamaulipas state (NE Mexico), spanning from about 30s decade of XX century until first years of the XXI, is made by means of multivaried statistical ...
Norma Sánchez Santillán +3 more
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