Results 111 to 120 of about 1,670,948 (272)
Faltwerk: a library for spatial exploratory data analysis of protein structures. [PDF]
Bioinform Adv, 2023 Viehweger A.
europepmc +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
An Exploratory Statistical Analysis of NASDAQ Provided Trade Data [PDF]
, 2014 Since Benoit Mandelbrot\u27s discovery of the fractal nature of financial price series, the quantitative analysis of financial markets has been an area of increasing interest for scientists, traders, and regulators.
Foley, Michael
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
SPACE-TIME LAGS: SPECIFICATION STRATEGY IN SPATIAL REGRESSION MODELS [PDF]
he purpose of this article is to analyse the dynamic trend of spatial dependence, which is not only contemporary but time-lagged in many socio-economic phenomena.
Coro Chasco Yrigoyen +1 more
core
The validity of smartphone data and its relationship to clinical symptomatology and brain biology: an exploratory analysis [PDF]
, 2018 BACKGROUND: Presently, there is very little research on the clinical validity of mental health smartphone application data, its relationship to brain biology, and its ability to inform clinical decisions.
Rizzuto, Conor
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Latin-American Journal of Computing, 2018 Technological development during the first decade of this century provoked a boom of user-generated, web-shared media. In geography, such trend is called Volunteered Geographic Information; OpenStreetMap (OSM) is its most famed project.
Roger Castro, Marco Luna
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source