Results 131 to 140 of about 1,902,848 (333)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Visualizing exploratory factor analysis models [PDF]

Exploratory factor analysis (EFA) is an important tool in data analyses, particularly in social science. Usually four steps are carried out which contain a large number of options.
Cornelia Wagner, Sigbert Klinke
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Validity & reliability of the Persian version of Grasha-Richmann student learning styles scale

Journal of Advances in Medical Education and Professionalism, 2013
Introduction: The present study aimed to investigate the psychometric properties of Grasha-Riechmann Student Learning Styles Scale. Method: The participants included 1039 students (421 students in human and 618 students in technical sciences ...
ALI REZA BANESHI, NOROUZ ALI KARAMDOUST, REZVAN HAKIMZADEH   +2 more
doaj  

Factorial validity and group invariance of the Portuguese short version of the Social Physique Anxiety Scale in adolescents [PDF]

, 2009
Social physique anxiety (SPA) has been associated with a range of psychosocial and health-related variables, thus it can be considered is an indicator of social-psychological adjustment.
Calmeiro, Luis, de Matos, Margarida. Gaspar, Simões, Celeste   +2 more
core  

Development of metacognitive skills inventory for internet search (MSIIS): Exploratory and confirmatory factor analyses

, 2018
This study reports the development of metacognition inventory for Internet search for middle school students. In this study, analysis and results of both exploratory and confirmatory factors are reported. Firstly, 37-items were generated considering literature review and metacognitive challenges faced during the search process, and pilot exploratory ...
Şendurur, Emine, Yıldırım, Zahide
openaire   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The Internal Structure of the WISC-V in Chile: Exploratory and Confirmatory Factor Analyses of the 15 Subtests

Journal of Intelligence
The WISC-V is a widely used scale in clinical and educational settings in Chile. Given that its use guides critical decision-making for children and adolescents, it is essential to have evidence of its psychometric properties, including validity based on
Marcela Rodríguez-Cancino, Andrés Concha-Salgado   +1 more
doaj   +1 more source