Results 131 to 140 of about 8,337,772 (301)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Validity & reliability of the Persian version of Grasha-Richmann student learning styles scale

Journal of Advances in Medical Education and Professionalism, 2013
Introduction: The present study aimed to investigate the psychometric properties of Grasha-Riechmann Student Learning Styles Scale. Method: The participants included 1039 students (421 students in human and 618 students in technical sciences ...
ALI REZA BANESHI, NOROUZ ALI KARAMDOUST, REZVAN HAKIMZADEH   +2 more
doaj  

Appendix – Supplemental material for Exploratory Factor Analyses of the Intelligence and Development Scales–2: Implications for Theory and Practice

, 2019
Supplemental material, Appendix for Exploratory Factor Analyses of the Intelligence and Development Scales–2: Implications for Theory and Practice by Silvia Grieder and Alexander Grob in ...
Alexander Grob (834416), Silvia Grieder (6643655)   +1 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Exploratory and Confirmatory Factor Analysis

, 2018
This chapter consists of data-driven examples of how factor analysis as a statistical tool can be applied in music education research. The chapter presents examples of how factor analysis methods can be used to identify latent variables, which in turn ...
Kenneth Elpus, Peter Miksza
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Adaptation, Development, and Validation of the Spiritual Community and Togetherness Scale (SCoTS)

Psychology International
We adapted the SCoTS from the Collegiate Psychological Sense of Community Scale to measure religious/spiritual (R/S) community and belonging among college students.
Christopher R. Dabbs, Carrie L. Winterowd, Elizabeth A. Albright, Tiffany Kolba, Tianna Etes, Bronson K. Snyder, Jeffery Logan Riddle, Kidist A. Beker   +7 more
doaj   +1 more source