Results 131 to 140 of about 8,922,367 (302)

Development of an empathy scale in nurses

open access: yesBMC Nursing
Objective To develop an empathy scale to measure the empathy in nurses. Materials and methods The sample of the study were collected between March and May in 2023 from 720 nurses working in private and state hospitals in İstanbul. Both exploratory factor
Funda Karaman   +6 more
doaj   +1 more source

Translation, content validity, and preliminary psychometric validation of the Existential Distress Scale in a Spanish non-clinical population

open access: yesFrontiers in Psychology
PurposeThis paper presents the adaptation, content validity assessment, and initial psychometric evaluation of the Existential Distress Scale (EDS) in a Spanish non-clinical sample. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA)
Susana Martínez Rodríguez   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Investigating the Psychometric Properties and Factor Structure of the Persian Version of Quantitative Assessment of Depressive Mixed state [PDF]

open access: yesTaḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: The aim of the present study was to examine the factor structure and psychometric properties of the Persian version of the quantitative assessment of depressive mixed state (DMX-12).
Maryam Faryabi, Nahid Akrami
doaj  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

K-DOCS-BRV: A Reduced and Validated Version of Kaufman’s Domains of Creativity Scale for Use in Brazil

open access: yesActa Colombiana de Psicología
Kaufman’s Domains of Creativity Scale (K-DOCS) assesses five areas of creativity, but its administration involves a 50-item questionnaire. This makes a shortened version necessary for time-limited research.
Felipe Alexandre de Souza Félix Nunes   +3 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Exploratory and confirmatory factor analyses of the Ukrainian version of CTSR Scale

open access: yes
The file contains raw data (n=619) for exploratory (n=200) and confirmatory factor (n=419) analyses, internal consistency (n=419), construct validity (n=419) and test-retest reliability (n=50).THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE ...
Zasiekina, L (via Mendeley Data)   +1 more
core   +1 more source

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