Results 191 to 200 of about 8,922,367 (302)

Integrative genomic SEM analysis of shared genetic architecture and candidate genes for insulin resistance-related metabolic traits. [PDF]

PLoS One
Li S, Liang Y, Zhu G, Wu L, Li H, Li Y, Chen Q.   +6 more
europepmc   +1 more source

Analysing the Factors Leading to Plagiarism Amongst Researchers: An Exploratory Approach

International Journal of Management Studies, 2018
openaire   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Selecting Between Whole-Sample and Split-Sample Strategies for Exploratory and Confirmatory Factor Analyses: Guidance for Psychometric Scale Development. [PDF]

Appl Psychol Meas
Arianpoor A, Webster CS, Taylor SCR, Shulruf B, Huang PH.   +4 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Initial Psychometric Evaluation of the Problematic Use of Generative Artificial Intelligence Scale Among Chinese School Students. [PDF]

Behav Sci (Basel)
Wang Y, Huang J, Wang DB, Shao H, Liu X, Ye T, Peng M, Yang H, Yu Y, Lau JTF.   +9 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Development and psychometric properties evaluation of individualized patient education tool: An exploratory sequential mixed-methods study protocol. [PDF]

PLoS One
Gardashkhani S, Ghafourifard M, Ghahramanian A, Ebadi A, Gilani N.   +4 more
europepmc   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Thrombophilic Variants and Clinical Outcomes in Young Ischaemic Stroke Patients Undergoing Mechanical Thrombectomy: A Retrospective Cohort Study. [PDF]

J Cardiovasc Dev Dis
Marzioglu Ozdemir E, Ozdemir G.
europepmc   +1 more source