Results 221 to 230 of about 304,850 (274)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Development of a brief stigma and perceptions questionnaire for pharmacists: An exploratory factor analysis approach in New York state counties enrolled in the healing communities study. [PDF]

J Subst Use Addict Treat
Goddard-Eckrich D, Grealis K, El-Bassel N, Lounsbury DW, Dsouza N, Bhuiyan J, Cervantes M, Angerame A, Feaster DJ, Kim E, Huang TTK, Sabounchi NS, Gilbert L, Levin FR, Edwards K, Gatanaga OS, McCrimmon T, David JL, Hunt T, Nunes EV, Wu E, Gutnick D, Rodriguez S, Gruss DE, Rodgers E, Campbell ANC, Xu J, Balise R.   +27 more
europepmc   +1 more source

The factorial validity and reliability of three versions of the Aggression Questionnaire using Confirmatory Factor Analysis and Exploratory Structural Equation Modelling

, 2015
Michael T. McKay, John L. Perry, Séamus Harvey   +2 more
openalex   +2 more sources

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Self-regulatory Sex Motives Scale in Online Dating: Exploratory Factor Analysis and Internal Consistency. [PDF]

Violence Against Women
Fereidooni F, Daniels JK, Lommen MJJ.
europepmc   +1 more source

Critical Success Factors in Social Public Security and Citizenship Programs: An Exploratory Analysis Of Public Policy Territories For Peace

Raimundo Nonato de Araújo Miranda Júnior, Iêdo Souza Santos, Antônio Erlindo Braga, Vitor William Batista Martins, André Cristiano Silva Melo   +4 more
openalex   +2 more sources

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Validity and reliability of a physical literacy knowledge, attitudes, self-efficacy and behaviors questionnaire for early childhood educators (PLKASB-ECE): An exploratory factor analysis. [PDF]

PLoS One
Lafave LMZ, Van Wyk N, Webster AD, Hayek J, Lafave MR.   +4 more
europepmc   +1 more source

Results of exploratory factor analysis and reliability tests of Mental Health Literacy Scale in the general public sample (N = 206); MHLS-Arabic-General Public.

Fareeda Abo-Rass (22693623), Ora Nakash (5323325), Sarah Abu-Kaf (10013567), Bizu Gelaye (370931), Hanan AboJabel (17629680), Anwar Khatib (22693626)   +5 more
openalex   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source