Results 91 to 100 of about 6,886,018 (279)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Uncovering the Psychometric Properties of Statistics Anxiety in Graduate Courses at a Minority-Serving Institution: Insights from Exploratory and Bayesian Structural Equation Modeling in a Small Sample Context

AppliedMath
The Statistics Anxiety Rating Scale (STARS) is a 51-item scale commonly used to measure college students’ anxiety regarding statistics. To date, however, limited empirical research exists that examines statistics anxiety among ethnically diverse or first-
Hyeri Hong, Ryan E. Ditchfield, Christian Wandeler   +2 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Factor Structure and Model Validation of Emotional Intelligence: An Exploratory and Structural Equation Modeling Approach

Journal of Nepal Commerce Association
The present study examined the level of emotional intelligence among higher secondary students in the Kottayam district using a descriptive survey research design. An adapted 15-item scale derived from the NHS Leadership Toolkit was administered to a stratified random sample of students from aided and unaided schools.
Soumya V, Santhos Kumar K
openaire   +1 more source

Instrumental Variables Two-Stage Least Squares (2SLS) vs. Maximum Likelihood Structural Equation Modeling of Causal Effects in Linear Regression Models

, 2019
In the presence of omitted variables or similar validity threats, regression estimates are biased. Unbiased estimates (the causal effects) can be obtained in large samples by fitting instead the Instrumental Variables Regression (IVR) model.
Shi, Dexin, Rosseel, Yves, Maydeu-Olivares, Alberto, Rosseel, YvesPP018010009749090000-0002-4129-4477F4D626CE-F0ED-11E1-A9DE-61C894A0A6B4   +3 more
core   +1 more source

Modeling Socially Desirable Responding and Its Effects [PDF]

, 2009
The impact of socially desirable responding or faking on noncognitive assessments remains an issue of strong debate. One of the main reasons for the controversy is the lack of a statistical method to model such response sets.
Matthias Ziegler, Ziegler, Matthias, Bühner, Markus, Markus Buehner   +3 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

A Pilot Study for Identification Responsible Food Consumption Determinants [PDF]

Journal of Agriculture and Rural Development Studies
The present study aimed to identify and interpret the determining factors of responsible behavior in food consumption, combining the theoretical analysis of the concept with an exploratory research study, followed by the analysis of results through ...
Maria Cristiana Garnai, Livia Patrascu, Adrian Micu   +2 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source