Results 171 to 180 of about 940,336 (300)

Advance Care Planning Among People With Dementia in the Netherlands: Insights From an Exploratory Survey of Health Care Professional Perspectives. [PDF]

open access: yesScand J Caring Sci
Vandaele LL   +7 more
europepmc   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Knowledge, attitudes and practices towards immunization among adult population in a tertiary care hospital-exploratory survey. [PDF]

open access: yesClin Exp Vaccine Res
Patlolla N   +11 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Patterns of pre-sleep music use and sleep quality: exploratory survey findings on state anxiety. [PDF]

open access: yesPeerJ
Danso A   +7 more
europepmc   +1 more source

Dementia and Firearms: an Exploratory Survey of Caregiver Needs [PDF]

open access: yesJournal of General Internal Medicine, 2019
Marian E, Betz   +6 more
openaire   +2 more sources

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