Results 61 to 70 of about 162,352 (215)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

The Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey

The Astrophysical Journal Letters
We present the Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey, a deep slitless spectroscopic and imaging Cycle 1 JWST treasury survey designed to constrain feedback mechanisms in low-mass galaxies across cosmic time. NGDEEP targets
Micaela B. Bagley, Nor Pirzkal, Steven L. Finkelstein, Casey Papovich, Danielle A. Berg, Jennifer M. Lotz, Gene C. K. Leung, Henry C. Ferguson, Anton M. Koekemoer, Mark Dickinson, Jeyhan S. Kartaltepe, Dale D. Kocevski, Rachel S. Somerville, L. Y. Aaron Yung, Bren E. Backhaus, Caitlin M. Casey, Marco Castellano, Óscar A. Chávez Ortiz, Katherine Chworowsky, Isabella G. Cox, Romeel Davé, Kelcey Davis, Vicente Estrada-Carpenter, Adriano Fontana, Seiji Fujimoto, Jonathan P. Gardner, Mauro Giavalisco, Andrea Grazian, Norman A. Grogin, Nimish P. Hathi, Taylor A. Hutchison, Anne E. Jaskot, Intae Jung, Lisa J. Kewley, Allison Kirkpatrick, Rebecca L. Larson, Jasleen Matharu, Priyamvada Natarajan, Laura Pentericci, Pablo G. Pérez-González, Swara Ravindranath, Barry Rothberg, Russell Ryan, Lu Shen, Raymond C. Simons, Gregory F. Snyder, Jonathan R. Trump, Stephen M. Wilkins   +47 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

EXPLORATORY LEARNING AND EMPLOYEE JOB PERFORMANCE: A STUDY IN VIETNAMESE HIGHER EDUCATION SETTING

Tạp chí Khoa học Đại học Đà Lạt, 2019
This paper aims to examine the effects of exploratory learning and risk taking on individual employee performance. The research question was empirically tested in the higher education setting using 181 survey questionnaires from academics of a top public
Trần Hà Minh Quân, Nguyễn Thị Nguyệt Quế   +1 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Preliminary validation of the PRImary care facility Management Evaluation tool (PRIME-Tool), a national facility management survey implemented in Ghana

BMC Health Services Research, 2019
Background The management quality of healthcare facilities has consistently been linked to facility performance, but available tools to measure management are costly to implement, often hospital-specific, not designed for low- and middle-income countries
Jhanna Uy, Erlyn K. Macarayan, Hannah L. Ratcliffe, Kate Miller, Easmon Otupiri, John Koku Awoonor-Williams, Lisa R. Hirschhorn, Stuart R. Lipsitz, Dan Schwarz, Asaf Bitton   +9 more
doaj   +1 more source