Results 31 to 40 of about 518,175 (290)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Evaluation of the Genotoxicity of Bangpungtongsung-San, a Traditional Herbal Prescription [PDF]

open access: yesPakistan Veterinary Journal, 2014
Bangpungtongsung-san (BPS) is a traditional Korean herbal formula used as an anti-inflammatory, antipyretic, antiobesity, and choleretic agent, which consists of 18 herbs.
In-Sik Shin   +6 more
doaj  

Bee Venom Protects against Rotenone-Induced Cell Death in NSC34 Motor Neuron Cells

open access: yesToxins, 2015
Rotenone, an inhibitor of mitochondrial complex I of the mitochondrial respiratory chain, is known to elevate mitochondrial reactive oxygen species and induce apoptosis via activation of the caspase-3 pathway. Bee venom (BV) extracted from honey bees has
So Young Jung   +3 more
doaj   +1 more source

Data Reduction Techniques for High Contrast Imaging Polarimetry. Applications to ExPo

open access: yes, 2011
Imaging polarimetry is a powerful tool for detecting and characterizing exoplanets and circumstellar environments. Polarimetry allows a separation of the light coming from an unpolarized source such as a star and the polarized source such as a planet or ...
Bagnulo   +23 more
core   +2 more sources

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

Online Pre-Events During the COVID-19 Pandemic

open access: yesInternational Journal of Communication, 2023
During the COVID-19 pandemic, mega-events such as the Olympics and expo were postponed, prolonging the build-up phase of the events and providing the opportunity to organize pre-events.
Luigi Di Martino, Lukasz Swiatek
doaj  

En’owkin Centre Breastfeeding Art Expo

open access: yesCanadian Food Studies, 2018
A unique Indigenous-focused Art Expo on the topic of breastfeeding was held at En’owkin Centre at Penticton Indian Band in October and November 2017. The En’owkin Centre is a nationally recognized Indigenous arts and training centre.
Karen Graham   +2 more
doaj   +1 more source

Changes in Transit Use and Service and Associated Changes in Driving Near a New Light Rail Transit Line, MTI Report 12-44 [PDF]

open access: yes, 2015
Los Angeles is pursuing possibly the most ambitious rail transit investment program in the nation with plans to open six new rail transit lines between now and 2019.
Boarnet, Marlon   +3 more
core   +1 more source

Risk management in a mega-project: the Universal EXPO 2015 case [PDF]

open access: yes, 2009
The paper analyses the literature on risk management in mega-projects suggesting possible mitigation actions to be considered in the stakeholders' management.
Locatelli, Giorgio, Mancini, Mauro
core   +1 more source

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