Results 31 to 40 of about 518,175 (290)
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Evaluation of the Genotoxicity of Bangpungtongsung-San, a Traditional Herbal Prescription [PDF]
Bangpungtongsung-san (BPS) is a traditional Korean herbal formula used as an anti-inflammatory, antipyretic, antiobesity, and choleretic agent, which consists of 18 herbs.
In-Sik Shin +6 more
doaj
Bee Venom Protects against Rotenone-Induced Cell Death in NSC34 Motor Neuron Cells
Rotenone, an inhibitor of mitochondrial complex I of the mitochondrial respiratory chain, is known to elevate mitochondrial reactive oxygen species and induce apoptosis via activation of the caspase-3 pathway. Bee venom (BV) extracted from honey bees has
So Young Jung +3 more
doaj +1 more source
Data Reduction Techniques for High Contrast Imaging Polarimetry. Applications to ExPo
Imaging polarimetry is a powerful tool for detecting and characterizing exoplanets and circumstellar environments. Polarimetry allows a separation of the light coming from an unpolarized source such as a star and the polarized source such as a planet or ...
Bagnulo +23 more
core +2 more sources
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Online Pre-Events During the COVID-19 Pandemic
During the COVID-19 pandemic, mega-events such as the Olympics and expo were postponed, prolonging the build-up phase of the events and providing the opportunity to organize pre-events.
Luigi Di Martino, Lukasz Swiatek
doaj
En’owkin Centre Breastfeeding Art Expo
A unique Indigenous-focused Art Expo on the topic of breastfeeding was held at En’owkin Centre at Penticton Indian Band in October and November 2017. The En’owkin Centre is a nationally recognized Indigenous arts and training centre.
Karen Graham +2 more
doaj +1 more source
Changes in Transit Use and Service and Associated Changes in Driving Near a New Light Rail Transit Line, MTI Report 12-44 [PDF]
Los Angeles is pursuing possibly the most ambitious rail transit investment program in the nation with plans to open six new rail transit lines between now and 2019.
Boarnet, Marlon +3 more
core +1 more source
Risk management in a mega-project: the Universal EXPO 2015 case [PDF]
The paper analyses the literature on risk management in mega-projects suggesting possible mitigation actions to be considered in the stakeholders' management.
Locatelli, Giorgio, Mancini, Mauro
core +1 more source

