Results 51 to 60 of about 630,752 (343)

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

100 % Fruit juice and measures of glucose control and insulin sensitivity: a systematic review and meta-analysis of randomised controlled trials

Journal of Nutritional Science, 2017
Studies on the effects of consuming 100 % fruit juice on measures of glycaemic control are conflicting. The purpose of the present study was to systematically review and quantitatively summarise results from randomised controlled trials (RCT) examining ...
Mary M. Murphy, Erin C. Barrett, Kara A. Bresnahan, Leila M. Barraj   +3 more
doaj   +1 more source

PEBBLING EXPONENTS OF PATHS [PDF]

Honam Mathematical Journal, 2010
Summary: A pebbling move on a connected graph \(G\) is taking two pebbles off of one vertex and placing one of them on an adjacent vertex. For a connected graph \(G\), \(G^p\) \((p>1)\) is the graph obtained from \(G\) by adding the edges \((u, v)\) to \(G\) whenever \(2\leq\text{dist}(u, v)\leq p\) in \(G\).
Kim, Ju Young, Kim, Sun Ah
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Revision arthroplasty after unicompartimental knee arthroplasty

Journal of Orthopaedic Surgery and Research, 2021
Background Unicompartimental knee arthroplasty (UKA) is a promising and increasing application to treat unicompartimental knee osteoarthritis. However, revision arthroplasty numbers after UKA are unknown. Therefore, aim of this study was to determine the
Nike Walter, Johannes Weber, Maximilian Kerschbaum, Edmund Lau, Steven M. Kurtz, Volker Alt, Markus Rupp   +6 more
doaj   +1 more source

The critical exponents of the two-dimensional Ising spin glass revisited: Exact Ground State Calculations and Monte Carlo Simulations [PDF]

, 1996
The critical exponents for $T\to0$ of the two-dimensional Ising spin glass model with Gaussian couplings are determined with the help of exact ground states for system sizes up to $L=50$ and by a Monte Carlo study of a pseudo-ferromagnetic order ...
Barahona F, Barahona F, Bray A J, Bray A J, Bray A J, Bray A J, Cheung H F, De Simone C, De Simone C, Dekker C, For site-disorder instead of bond disorder there are indications of a finite temperature phase transition in 2d: Shirakura T, G Rinaldi, Grötschel M, H Rieger, Jünger M, Karp R M, Kawashima N, Kawashima N, Kisker J, L Santen, M Diehl, M Jünger, Rieger H, U Blasum   +23 more
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Evaluation of Fire Spread and Suppression Techniques in Micro-Mobility Battery Packs

ECS Advances
Lithium-ion battery packs used in micro-mobility devices, such as e-bikes and e-scooters can lead to substantial safety hazards should a single cell go into thermal runaway.
Daniel A. Torelli, Nicholas Faenza, Phil Johns, Sam Lawton, James Frake   +4 more
doaj   +1 more source

Critical crack path assessments in failure investigations [PDF]

Fracture and Structural Integrity, 2015
This paper presents a case study in which identification of the controlling crack path was critical to identifying the root cause of the failure. The case involves the rupture of a 30-inch (0.76 m) natural gas pipeline in 2010 that tragically led to ...
Robert D. Caligiuri
doaj   +1 more source

Critical exponents of the driven elastic string in a disordered medium

, 2005
We analyze the harmonic elastic string driven through a continuous random potential above the depinning threshold. The velocity exponent beta = 0.33(2) is calculated.
H. Gao, Olaf Duemmer, S. Moulinet, T. Nattermann, Werner Krauth   +4 more
core   +1 more source