Results 41 to 50 of about 14,393,463 (300)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Reactimeter dispersion equation
The aim of this work is to derive and analyze a reactimeter metrological model in the form of the dispersion equation which connects reactimeter input/output signal dispersions with superimposed random noise at the inlet.
A.G. Yuferov
doaj +1 more source
EXPONENTIAL DISPERSION MODELS AND THE GAUSS‐NEWTON ALGORITHM [PDF]
SummaryIt is known that the Fisher scoring iteration for generalized linear models has the same form as the Gauss‐Newton algorithm for normal regression. This note shows that exponential dispersion models are the most general families to preserve this form for the scoring iteration. Therefore exponential dispersion models are the most general extension
openaire +3 more sources
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Ion temperature gradient mode and its solitons with regularized κ-distributed electrons
The linear and the non-linear behaviors of the ion temperature gradient (ITG) mode in a plasma with regularized κ-distributed electrons are investigated using the fluid model.
J. Zhou +3 more
doaj +1 more source
The perturbed nonlinear Schrödinger (NLS) equation and the nonlinear radial dislocations model in microtubules (MTs) are the underlying frameworks to simulate the dynamic features of solitons in optical fibers and the functional aspects of microtubule ...
M. Ali Akbar +8 more
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Accurately predicting the remaining useful life (RUL) of critical mechanical components is a central challenge in reliability engineering. Stochastic processes, which are capable of modeling uncertainties, are widely used in RUL prediction.
Jiayue Wu +4 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source

